This piece goes on to the actual excel connection provider.
Provider=Microsoft.Jet.OLEDB. 4.0;Data Source=C:\Temp\<FILENAME.xls>;Extended Properties="EXCEL 8.0;HDR=YES;IMEX=1";
Instead of table loading the excel file on the datasource, utlize a SQL query such as this.
SELECT F1,F18 from [Sheet1$A3:D8]
WHERE
F1 IS NOT NULL
........