SharePoint & Antivirus

Folders to consider for exclusion in antivirus programs:

C:\Program Files\Microsoft Office Servers\14.0\Logs
C:\Program Files\Microsoft Office Servers\
C:\Program Files\Common Files\Microsoft Shared\Web Server Extensions\14\LOGS
C:\Program Files\Common Files\Microsoft Shared\Web Server Extensions\

C:\Program Files\Microsoft SQL Server
C:\Program Files (x86)\Microsoft SQL Server

Sources:

• http://support.microsoft.com/kb/952167
• http://social.technet.microsoft.com/wiki/contents/articles/953.microsoft-anti-virus-exclusion-list.aspx
• http://support.microsoft.com/kb/309422

Antivirus Software

I am asked all the time for assistance with home antivirus. Here are some free options:
Avast  (I use this)
Microsoft Security Essentials  (I use this. Yes... I run two antivirus programs)
Avira
Malwarebytes
AVG
Panda - Cloud and Free Tools

If you feel the need to drop money on antivirus here are some options:
Kapersky
Panda
Norton (I don't recommend it and I won't even link to it)
F-Secure
G Data

Last but not least, practice good browsing habits and back your data up with some level of regularity.