Folders to consider for exclusion in antivirus programs:
C:\Program Files\Microsoft Office Servers\14.0\Logs
C:\Program Files\Microsoft Office Servers\
C:\Program Files\Common Files\Microsoft Shared\Web Server Extensions\14\LOGS
C:\Program Files\Common Files\Microsoft Shared\Web Server Extensions\
C:\Program Files\Microsoft SQL Server
C:\Program Files (x86)\Microsoft SQL Server
Sources: